OpenAI is seeing a wave of senior departures and reassignments as the company moves toward a public offering.

According to the New York Post, Fidji Simo — described as Sam Altman's "right-hand woman" — is stepping down from OpenAI due to chronic illness, with her exit coming ahead of the company's IPO.

Her departure leaves a gap at the top of OpenAI's product operation. According to PYMNTS.com, co-founder Greg Brockman is taking over the product business that Simo had been running.

The changes aren't limited to the product side. According to Wired, Johannes Heidecke, OpenAI's head of safety, is also leaving the company. Wired reports that his departure comes as OpenAI works to further integrate its research and safety teams — a sign the company is reorganizing how it handles the risks of its technology, not just who ships its products.

Taken together, the moves show OpenAI rearranging its leadership at a pivotal moment. Product, safety, and executive functions are all in flux at once, and a co-founder is stepping back into day-to-day operational responsibility.

Why it matters: OpenAI is one of the most influential companies in artificial intelligence, and how it structures its product and safety leadership on the eve of a public listing will shape both its business and the guardrails around technology that millions of people already use.