Nvidia has tightened its grip on high-performance computing, the field that powers everything from climate modeling to drug discovery to artificial intelligence research.

According to Nvidia, its technology now runs more than 400 of the world's 500 fastest supercomputers. The company says it powers 81% of the systems on the TOP500, a closely watched ranking of the most powerful machines on the planet. Its lead among the newest hardware is even stronger: Nvidia reports that 90% of the systems newly added to the list rely on its technology.

The figures, released around the ISC 2026 conference, also point to growing traction for Nvidia's own central processors, not just its graphics chips. The company says 26 systems on the TOP500 have adopted the Nvidia Grace CPU, up eight from the previous edition of the list.

Nvidia also highlighted its standing on the Green500, a companion ranking that measures energy efficiency rather than raw speed. According to Nvidia, the top eight systems on the Green500 run on its GPUs, and nine of the top 10 use Nvidia technologies.

These rankings matter because supercomputers are the engines behind modern scientific research and the training of large AI models, and energy efficiency increasingly determines what is affordable to build and operate. The numbers come directly from Nvidia, so they reflect the company's own accounting of its market position rather than an independent audit.

Still, the breadth of the claims underscores how central one company's chips have become to the infrastructure of advanced computing — a concentration that shapes who can compete at the frontier of science and AI.